Yields and purities of individual BERAs produced on a large scale using the nCAR platform and isolated by FPLC method
| nCAR | Yield | Purity |
|---|---|---|
| mg RNA/l fermentation | %; by HPLC | |
| miR-27a-3p | 10.1 | 99.4 |
| miR-27b-3p | 10.2 | 99.4 |
| miR-451a-5p | 18.8 | 98.9 |
| ApoB-siRNA | 17.0 | 99.0 |
| anti-miR-126-3p | 20.0 | 99.2 |
| ICAM1-siRNA | 12.0 | 98.6 |
| miR-298-5p | 15.4 | 97.2 |
| miR-519c-5p | 16.0 | 99.3 |
| miR-122-5p | 9.80 | 87.0 |
| Nrf2-siRNA | 18.7 | 98.3 |
| miR-126-3p | 11.6 | 99.8 |
| miR-144-5p | 10.6 | 98.7 |
| ARV7-siRNA | 17.0 | 99.3 |
| GFP-siRNA | 12.0 | 99.3 |
| let-7c-5p | 8.70 | 92.4 |
| miR-127-3p | 3.83 | 95.5 |
| miR-34a-5p | 16.6 | 98.3 |
| miR-124-3p | 8.34 | 98.3 |
| miR-328-3p | 14.8 | 99.7 |
| anti-miR-451b-5p | 11.3 | 99.3 |
| MSA | 5.72 | 99.6 |
| anti-miR-21-5p-3 | 7.48 | 98.2 |
| miR-33a-5p | 7.54 | 96.0 |
| anti-miR-21-5p-2 | 9.41 | 96.9 |
| anti-miR-122-5p | 7.67 | 99.3 |
| scrm-5 | 7.54 | 53.5 |
| scrm-4 | 7.43 | 98.2 |
| scrm-3 | 8.54 | 99.3 |
| anti-miR-21-5p | 11.7 | 99.4 |
| miR-34a/TPA3′+TPA5′ | 18.2 | 99.5 |
| miR-888/pegaptanib3′ | 16.0 | 98.3 |
| miR-34a/EpCAMA3′ | 12.7 | 99.0 |