Metabolic parameters of mice in both control and indomethacin-treated groups
| Metabolic Parameter | Control | Indomethacin | P value |
|---|---|---|---|
| Body weight (g) | 30.73 ± 1.57 | 31.30 ± 2.04 | 0.41 |
| Body composition | |||
| Fat mass (%) | 19.62 ± 3.05 | 13.32 ± 3.07 | 0.23 |
| Lean mass (%) | 79.51 ± 3.19 | 83.47 ± 2.88 | 0.20 |
| BAT of body weight (%) | 0.32 ± 0.01 | 0.28 ± 0.16 | 0.03 |
| rWAT of body weight (%) | 0.95 ± 0.17 | 0.81 ± 0.25 | 0.34 |
| eWAT of body weight (%) | 3.41 ± 0.64 | 2.25 ± 0.66 | 0.14 |
| iWAT of body weight (%) | 1.24 ± 0.38 | 1.29 ± 0.09 | 0.44 |
| Food intake (g/day) | 2.91 ± 0.16 | 3.02 ± 0.18 | 0.34 |
| Fasting glucose (mg/dl) | 229.30 ± 6.84 | 185.00 ± 13.58 | 0.02 |
| Blood lipid profile | |||
| TG (mg/dl) | 95.00 ± 5.00 | 85.00 ± 2.89 | 0.07 |
| TC (mg/dl) | 160.00 ± 32.79 | 133.30 ± 11.67 | 0.24 |
| LDL-C (mg/dl) | 63.33 ± 28.48 | 41.67 ± 7.27 | 0.25 |
| VLDL-C (mg/dl) | 18.33 ± 1.67 | 16.67 ± 1.67 | 0.26 |
| HDL-C (mg/dl) | 77.50 ± 5.35 | 74.67 ± 4.51 | 0.35 |
| NEFA (nm/ml) | 13.97 ± 0.49 | 13.88 ± 1.18 | 0.47 |
All data are expressed as mean ± SEM (n=3) and analyzed by student t tests. Abbreviations: rWAT, retroperitoneal white adipose tissue; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; NEFA, nonesterified fatty acids; TC, total cholesterol; TG, triglyceride; VLDL-C, very low-density lipoprotein cholesterol.