Demographic and clinicopathologic characteristics of the control subjects (n = 95) and HCC patients (n = 67)
Mann-Whitney U test and χ2 test were used.
| Clinicopathologic characteristics | Control | HCC | P Value |
|---|---|---|---|
| Gender | |||
| Male (n, %) | 33 (34.7) | 56 (83.6) | <0.0001 |
| Female (n, %) | 62 (65.3) | 11 (16.4) | |
| Age (years) | 0.011 | ||
| ≤50 (n, %) | 63 (66.3) | 31 (46.3) | |
| >50 (n, %) | 32 (33.7) | 36 (53.7) | |
| Body weight [median (range)] | 63.5 (30–92) | 66 (35–101) | 0.11 |
| HBsAg | <0.0001 | ||
| Negative (n, %) | 95 (100) | 3 (4.5) | |
| Positive (n, %) | 0 (0) | 64 (95.5) | |
| HCV | 0.23 | ||
| Negative (n, %) | 95 (100) | 66 (98.5) | |
| Positive (n, %) | 0 (0) | 1 (1.5) | |
| Diagnosis | |||
| Liver hemangioma (n = 61) | HCC (n = 67) | ||
| Metastatic carcinoma (n = 9) | |||
| Cholelithiasis (n = 7) | |||
| Gallbladder cancer (n = 13); other (n = 5) | |||
| Serum AFP (ng/ml) | <0.0001 | ||
| ≤600 (n, %) | 54 (100) | 31 (52.6) | |
| >600 (n, %) | 0 (0) | 28 (47.4) | |
| Tumor size (cm) | |||
| ≤5 (n, %) | 16 (24.6) | ||
| >5 (n, %) | 49 (75.4) | ||
| Multinodular tumors | |||
| Yes (n, %) | 26 (40.0) | ||
| No (n, %) | 39 (60.0) | ||
| Tumor grade | |||
| I and II (n, %) | 29 (44.6) | ||
| III and IV (n, %) | 36 (55.4) | ||
| Metastasis | |||
| Yes (n, %) | 4 (6.2) | ||
| No (n, %) | 61 (93.8) | ||
| Portal vein tumor thrombus | |||
| Yes (n, %) | 16 (24.6) | ||
| No (n, %) | 49 (75.4) | ||
| Splenomegaly | |||
| Yes (n, %) | 18 (27.7) | ||
| No (n, %) | 47 (72.3) |
AFP, alpha-fetoprotein; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus.