TABLE 1

Effects of curcumin on motor activity and coordination of mice

ICR mice were placed into photocell activity cages for 30 minutes or placed on the rotarod for 3 minutes after 45-minute i.p. administration of curcumin (30 mg/kg). Data are presented as the mean ± S.E.M. as the number of photocell interruptions and time to fall in percentage impairment for each group, respectively (5–6).

TreatmentSpontaneous ActivityRotarod Activity
# Interrupts/30 min% Impairment
Vehicle1018 ± 146.717.3 ± 10.3
Curcumin1125 ± 111.512.5 ± 12.5