TABLE 3

Pharmacokinetic parameters of tegoprazan in dog

Data represent mean (S.D.) of three animals.

DoseCmaxTmaxt1/2AUC1-inf
mg/kgng/mlhhng·h per milliliter
0.3224 (11.0)0.750 (0.433)3.43 (0.132)1181 (530)
32490 (420)0.500 (0.00)3.30 (0.759)12,731 (6180)
3023,833 (2438)1.08 (0.878)3.52 (0.280)163,951 (28,969)