The IC50 values of tegoprazan in the in vitro studies
The data for H+/K+-ATPase show the mean values (95% confidence interval) from three independent experiments. Three experiments for canine Na+/K+-ATPase resulted in IC50 > 100 μM.
| H+/K+-ATPase | Na+/K+-ATPase (Canine) | ||||
|---|---|---|---|---|---|
| Ion Leakey | Ion Tight | ||||
| Porcine | Canine | Human | Porcine | ||
| Tegoprazan (μM) | 0.47 (0.42, 0.52) | 0.29 (0.27, 0.31) | 0.52 (0.50, 0.53) | 0.13 (0.12, 0.14) | >100 |