TABLE 3

Parameter values for the dynamics of GILZ mRNA expression

ParameterDefinitionEstimate (CV%)
a0,GILZmFourier coefficient for GILZ mRNA14,002a/6479b/9845c
a1,GILZmFourier coefficient for GILZ mRNA−3447a/1133b/-441c
b1,GILZmFourier coefficient for GILZ mRNA−8339a/-1651b/−5148c
kd,GILZm (h−1)Degradation rate constant for GILZ mRNA0.45a (7.7)/0.16b (14.3)/0.21c (5.8)
SDRnGILZm (nM−1)Stimulation of GILZ mRNA production0.47a (6.8)/0.27b (40.0)/0.3c (8.3)
GILZmMPL (0) (mol/ng RNA)GILZ mRNA initial concentration (treatment)10,560a (fixed)/4249b (17.9)/6077c (21.3)