APAP clearance | 0.03 | 0.74 | −0.01 | 0.89 | −0.40 | <0.001 | −0.03 | 0.81 | 0.03 | 0.78 | 0.17 | 0.006 |
Glucuronidation clearance | 0.04 | 0.72 | −0.08 | 0.45 | −0.53 | <0.001 | 0.02 | 0.86 | 0.09 | 0.33 | 0.29 | <0.001 |
Glucuronide/APAP AUC | 0.04 | 0.67 | −0.26 | 0.008 | −0.51 | <0.001 | −0.01 | 0.89 | 0.08 | 0.40 | 0.31 | <0.001 |
Sulfation clearance | 0.23 | 0.04 | 0.03 | 0.80 | −0.06 | 0.59 | −0.12 | 0.30 | −0.13 | 0.23 | 0.08 | 0.20 |
Sulfate/APAP AUC | 0.17 | 0.11 | −0.20 | 0.07 | −0.01 | 0.89 | −0.21 | 0.06 | −0.05 | 0.65 | 0.12 | 0.05 |
Oxidation clearance | −0.36 | <0.001 | 0.12 | 0.25 | 0.09 | 0.34 | 0.06 | 0.55 | −0.23 | 0.02 | 0.23 | <0.001 |
APAP protein-adduct | −0.08 | 0.44 | 0.04 | 0.72 | 0.37 | <0.001 | −0.18 | 0.09 | −0.17 | 0.10 | 0.19 | 0.003 |