TABLE 1

In vitro binding profile of GW405833

Ki (nM)rCB2/rCB1 SelectivityAssayReference
hCB1hCB2hCB2/hCB1 SelectivityrCB1rCB2
47723.9212172733.676[3H] CP55,940 bindingValenzano et al., 2005
2827.6237NA11.1NA[3H] CP55,940 bindingYao et al., 2008
191712160NANANA[3H] WIN55,212-2 bindingGallant et al., 1996
  • NA, not available; hCB, human cannabinoid receptor; rCB, rat cannabinoid receptor.