TABLE 3 

Pharmacokinetic parameters after rats received a 50 mg/kg oral dose of LX2761 or sotagliflozin

CompoundNHalf-LifeTmaxCmaxAUC0–lastAUC0–∞%F
hrhrnMnM*hrnM*hr%
LX27615N/A0.6 ± 0.237 ± 27424 ± 134N/A<5
Sotagliflozin42.42 ± 0.081.88 ± 1.5511918 ± 625052027 ± 672252103 ± 671256 ± 7
  • N, number of animals; %F, % bioavailable; N/A, value could not be calculated owing to low exposure.