Summary of model development based on AIC values
| Pancreas | Ovarian | ||||||
|---|---|---|---|---|---|---|---|
| KP4 | ASPC1 | MIA PACA2 | PANC1 | SKOV3×luc | A2780 | ||
| Description | AIC | AIC | AIC | AIC | AIC | AIC | |
| Disease progression | Exponential | −192.798 | −172.815 | −489.66 | −256.725 | −253.548 | −181.226 |
| Gompertz | −117.969 | −163.456 | −314.717 | −254.725 | −275.884 | −219.434 | |
| Simeoni | −188.827 | −172.57 | −718.093 | −256.786 | −282.99 | −163.86 | |
| Hahnfeldt | −283.535 | −196.043 | −795.107 | −287.133 | −289.894 | −233.267 | |
| Hahnfeldt covariate T0 | — | — | — | — | −318.606 | — | |
| Hahnfeldt covariate T0 & λ1 | — | — | — | — | −335.02 | — | |
| Gemcitabine effects | Apoptotic effect on tumor volume | −625.927 | −234.289 | −1232.49 | −527.143 | −480.371 | 345.295 |
| + Effect on carrying capacity | −632.2 | −250.761 | −1297.358 | −567.945 | −570.865 | 211.292 | |
| + EMAX model on apoptotic effect | — | — | — | — | −677.887 | −77.724 | |
| Carboplatin effects | No carboplatin effect (all driven by gemcitabine) | — | — | — | — | −585.679 | 158.691 |
| Apoptotic effect on tumor volume | — | — | — | — | −583.63 | −110.775 | |
| Effect on carrying capacity | — | — | — | — | −594.739 | −346.857 | |