TABLE 3

Comparison of urinary excretion of CPs I and III in cynomolgus monkeys, mice, and humans

Species (n)	X_{e (0–24 h)} (Body Weight)			Total Urinary CP		Urinary CP Ratio
Species (n)	CP I	CP III	Total CP	CP I	CP III	CP I/CP III
	nmol/kg	nmol/kg	nmol/kg	%	%
Monkey experiment 1 (3)	0.37 ± 0.14	4.42 ± 1.23	4.79 ± 1.35	7.6 ± 1.4	92.4 ± 1.4	0.08 ± 0.02
Monkey experiment 2 (3)	0.15 ± 0.10	2.14 ± 1.43	2.29 ± 1.53	6.7 ± 0.58	93.3 ± 0.58	0.07 ± 0.01
Mouse (3)	0.34 ± 0.06	0.91 ± 0.17	1.25 ± 0.22	27.2 ± 2.2	72.8 ± 2.2	0.37 ± 0.04
Human^{^a} (30)	0.30 ± 0.09	1.17 ± 0.44	1.46 ± 0.50	N.D.	78.2 ± 5.8	N.D.
Human^{^b} (22)	0.48 ± 0.24	1.13 ± 0.35	1.57 ± 0.46	N.D.	71.0 ± 10.2	0.44 ± 0.25
Human^{^c} (86)	0.31	1.10	1.41	22.2	77.8	0.29

N.D., not determined.
↵^a Data on urinary excretion of CPs I and III in healthy subjects are from Koskelo et al. (1967).
↵^b Data on urinary excretion of CPs I and III in healthy subjects are from Koskelo et al. (1966).
↵^c Data on urinary excretion of CPs I and III in healthy subjects are from Gebril et al. (1990).