TABLE 1

GABA mIPSC decay kinetics after exposure to PKA modulators and ethanol

Data are presented as means ± S.E.M.

MeasureControlEthanolEthanol Plus CalCEthanol Plus Rp-cAMPEthanol Plus Rolipram
Rise time (ms)2.4 ± 1.03.1 ± 1.42.8 ± 0.91.9 ± 1.02.6 ± 0.6
Amplitude (pA)22.1 ± 1.223.5 ± 1.022.8 ± 1.921.6 ± 0.922.5 ± 1.1
Frequency (Hz)1.9 ± 0.41.5 ± 0.82.1 ± 0.61.8 ± 0.42.0 ± 0.5
Decay τ119.4 ± 1.012.5 ± 1.3*19.6 ± 1.312.4 ± 1.4*19.5 ± 1.6
Decay τ230.1 ± 2.332.1 ± 2.631.2 ± 2.532.0 ± 1.931.6 ± 1.4
Number1411111111
  • * P < 0.05 (compared with control, ethanol plus CalC, or ethanol plus rolipram groups, one-way ANOVA, Bonferroni post-test).