TABLE 1

Cumulative excretion of radioactivity in the bile, urine, and feces of bile duct–cannulated cynomolgus monkeys (n = 3) after a single oral administration of [³H]RSV

Data are reported as mean ± S.D., n = 3 different animals.

Collection Interval	Excretion of Radioactivity (% of Dose)
Collection Interval	Bile	Urine	Feces
h
0–8	20.8 ± 7.3	0.9 ± 0.3	NS^{^a}
8–24	13.5 ± 4.4	0.7 ± 0.2	30.1 ± 5.5
24–72	4.7 ± 2.9	0.8 ± 0.5	20.5 ± 17.0
72–168	NS^{^b}	0.6 ± 0.3	11.2 ± 12.4
0–168	39.0 ± 3.0	2.9 ± 1.3	61.7 ± 25.1
Total recovery		103.6 ± 27.5

NS, no sample.
↵^a Only 0- to 24-hour fecal samples were collected and analyzed.
↵^b Only 0- to 72-hour bile samples were collected and analyzed.