TABLE 2

Effect of aerosolized cannabinoids on the total number of coughs in guinea pigs in response to aerosolized citric acid

Each animal was initially exposed to aerosolized citric acid (0.3 M) for 15 minutes to determine the number of coughs elicited in the absence of test substances (screen). After 4 days, half of the animals in a group were either exposed to an aerosolized cannabinoid (10 mg/ml) or its vehicle, solutol, for 20 minutes. Thirty minutes later, the animals were challenged with citric acid (0.3 M) and the number of coughs was counted. This was repeated 4 days later but with animals crossed over to treatment. Each value represents the mean ± S.E.M. (n = 8 animals).