PEGylated liposomal doxorubicin plasma PK parameters in patients with recurrent EOC
| Parameter | Encapsulated | Released | Ratio of AUCreleased to AUCencapsulated | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CL | AUC | t1/2 | Vd | CL | AUC | t1/2 | Vd | ||
| ml/h | ng/ml*h | h | ml | ml/h | ng/ml*h | h | ml | ng/ml*h | |
| Mean ± S.D. | 25.7 ± 12.1 | 2,898,782 ± 974,518 | 79.6 ± 25.3 | 2,569 ± 502 | 253.0 ± 175.8 | 243,541 ± 171,578 | 189.7 ± 252.6 | 40,166 ± 34,838 | 0.10 ± 0.05 |