Effect of adenosine receptor agonists on CRE-dependent transcription in 6×CRE BEAS-2B luciferase reporter cells
Treatment | N | p[A]50 | Maximum Fold Induction |
---|---|---|---|
Bay 60-6583 | 17 | −7.96 ± 0.11 | 15.5 ± 0.8 |
NECA | 8 | −6.74 ± 0.14 | 13.9 ± 0.5 |
CV 1808 | 3 | >–5.5a | 10.1 ± 1.0a |
CGS 21680 | 7 | >–5.0a | 8.8 ± 1.4a |
↵a Full E/[A] curves could not be determined. Fold enhancement is that produced by 10 and 30 μM CV 1808 and CGS 21680, respectively. Data calculated from Fig. 2A.