Summary of baseline characteristics (± S.E.M.) before chronic dosing in 5/6 nephrectomized rats
Differences not significant for any treatment within a given parameter.
| Parameter | Vehicle (n = 12) | 0.3 mg/kg (n = 12) | 1 mg/kg (n = 12) | 3 mg/kg (n = 12) |
|---|---|---|---|---|
| PTH (pg/ml) | 1089 ± 75 | 1074 ± 101 | 1117 ± 131 | 1101 ± 88 |
| Creatinine (mg/dl) | 1.09 ± 0.04 | 1.07 ± 0.03 | 1.06 ± 0.03 | 1.08 ± 0.04 |
| Body weight (g) | 316 ± 3 | 317 ± 4 | 325 ± 5 | 324 ± 6 |