TABLE 2

Summary of baseline characteristics (± S.E.M.) before acute dosing in 5/6 nephrectomized rats, day 1

Differences not significant for any treatment within a given parameter.

Parameter0.3 mg/kg (n = 5)1 mg/kg (n = 5)3 mg/kg (n = 5)
PTH (pg/ml)808 ± 199793 ± 163724 ± 73
Creatinine (mg/dl)0.87 ± 0.030.88 ± 0.080.88 ± 0.07
Body weight (g)328 ± 11340 ± 13321 ± 5