Summary of baseline characteristics (± S.E.M.) before acute dosing in 5/6 nephrectomized rats, day 1
Differences not significant for any treatment within a given parameter.
| Parameter | 0.3 mg/kg (n = 5) | 1 mg/kg (n = 5) | 3 mg/kg (n = 5) |
|---|---|---|---|
| PTH (pg/ml) | 808 ± 199 | 793 ± 163 | 724 ± 73 |
| Creatinine (mg/dl) | 0.87 ± 0.03 | 0.88 ± 0.08 | 0.88 ± 0.07 |
| Body weight (g) | 328 ± 11 | 340 ± 13 | 321 ± 5 |