Group | 1-Month | 2-Month | 3-Month | Average |
---|---|---|---|---|
Luseogliflozin Intake (mg/kg) | ||||
Luseogliflozin | 15.5 ± 1.6 | 14.2 ± 1.0 | 14.6 ± 0.5 | 14.8 ± 0.9 |
Combination | 13.9 ± 1.0 | 13.0 ± 0.4 | 13.6 ± 1.0 | 13.5 ± 0.4 |
Lisinopril Intake (mg/kg) | ||||
Lisinopril | 12.4 ± 1.1 | 9.8 ± 0.8 | 9.5 ± 1.3 | 10.5 ± 0.9 |
Combination | 14.1 ± 0.3 | 9.2 ± 0.3 | 8.6 ± 0.7 | 10.7 ± 0.3 |
Plasma Luseogliflozin Concentration (ng/ml) | ||||
Luseogliflozin | 65.9 ± 4.9 | 50.0 ± 10.1 | 56.1 ± 13.5 | 57.3 ± 7.8 |
Combination | 61.2 ± 7.3 | 49.5 ± 6.1 | 31.0 ± 3.7 | 47.2 ± 4.5 |