TABLE 2

Effects of JNJ1625985 on environmentally directed behaviors

TreatmentLocomotionForagingObject Exploration
Vehicle8 ± 1.80.2 ± 0.033.8 ± 3.5
0.18 mg/kg JNJ16259850.4 ± 0.6*0.2 ± 0.020.1 ± 0.1
0.3 mg/kg JNJ16259850.9 ± 0.8*0.1 ± 0.010.1 ± 0.3
0.56 mg/kg JNJ16259850.5 ± 0.5*0.1 ± 0.050.3 ± 0.8
  • * , P < 0.05, effects of pretreatment with JNJ16259685 compared with pretreatment with vehicle; Bonferroni t test.