TABLE 2

Characteristics of GABAergic PSCs recorded from CA1 pyramidal neurons in hippocampal slices incubated with TTX (200 nM) alone or together with MLA (10 nM)

Data are presented as mean ± S.E.M. of results obtained from five neurons from five rats in control, 10 neurons from six rats in TTX, and six neurons from four rats in TTX plus MLA.

TreatmentAmplitudeRise Time 10 to 90%τd
pAms
ACSF26.5 ± 0.692.19 ± 0.1834.8 ± 1.59
200 nM TTX13.4 ± 0.52**1.87 ± 0.1538.6 ± 2.98
200 nM TTX plus 10 nM MLA14.1 ± 0.84**1.81 ± 0.2439.9 ± 3.04
  • ** P < 0.01 compared with control according to one-way ANOVA followed by Dunnett post hoc test.