Physiologic values for 90-min MCAO, treatment onset 5 min after reperfusion onset
All values are mean ± S.D.
| Vehicle | MnTnHex-2-PyP | |
|---|---|---|
| n | 17 | 18 |
| Preischemia body weight, g | 255 ± 14 | 262 ± 14 |
| Body weight 7 days after ischemia, g | 239 ± 51 | 275 ± 32* |
| Body weight change, g | −17 ± 47 | +14 ± 27* |
| 10 min preischemia, g | ||
| MAP, mm Hg | 81 ± 10 | 83 ± 7 |
| Arterial pH | 7.44 ± 0.04 | 7.43 ± 0.04 |
| PaCO2, mm Hg | 38 ± 4 | 35 ± 3* |
| PaO2, mm Hg | 163 ± 27 | 156 ± 23 |
| Blood glucose, mg/dl | 75 ± 11 | 72 ± 8 |
| Hematocrit, % | 42 ± 2 | 41 ± 2* |
| Pericranial temperature, °C | 37.5 ± 0.1 | 37.5 ± 0.1 |
| 45 min after ischemia onset | ||
| MAP, mm Hg | 76 ± 13 | 75 ± 10 |
| Arterial pH | 7.41 ± 0.05 | 7.41 ± 0.07 |
| PaCO2, mm Hg | 39 ± 6 | 38 ± 5 |
| PaO2, mm Hg | 167 ± 13 | 160 ± 17 |
| Pericranial temperature, °C | 37.5 ± 0.1 | 37.5 ± 0.1 |
| 10 min after ischemia | ||
| MAP, mm Hg | 73 ± 6 | 72 ± 7 |
| Arterial pH | 7.39 ± 0.06 | 7.38 ± 0.07 |
| PaCO2, mm Hg | 40 ± 5 | 39 ± 6 |
| PaO2, mm Hg | 173 ± 13 | 171 ± 15 |
| Pericranial temperature, °C | 37.5 ± 0.1 | 37.5 ± 0.1 |
* P < 0.05.