Inhibitory effects of nortriptyline and LY294002 on EC50 and Emax of budesonide
| Effects of Nt | Effects of LY294002 | ||||||
|---|---|---|---|---|---|---|---|
| Control | CSE | CSE +Nt (3.3 μM) | CSE +Nt (1 μM) | Control | CSE | CSE +LY294002 (1 μM) | |
| EC50 (nM) | 0.85 | 5.9 | 1.00 | 0.54 | 1.28 | 2.67 | 1.07 |
| Emax (%) | 56 ± 5 | 24 ± 2 | 32 ± 8 | 33 ± 6 | 49 ± 6 | 12 ± 3 | 18 ± 4 |