Physiological parameters determined in rats after 2 weeks of administration of control or fructose-containing drinking water Rats were given normal drinking water (control) or fructose-containing drinking water (10% fructose) for a period of 2 weeks, after which time these parameters were assessed.
Variable | Control Group (n = 18) | Fructose-Treated Group (n = 20) |
|---|---|---|
| Systolic blood pressure (mm Hg) | 119.4 ± 1.1 | 134.3 ± 1.2* |
| Glucose (mM) | 4.36 ± 0.20 | 4.57 ± 0.28 |
| Triglyceride (mM) | 0.47 ± 0.23 | 0.98 ± 0.51* |
| Cholesterol (mM) | 1.35 ± 0.17 | 1.49 ± 0.25 |
| Insulin (mIU/l) | 9.63 ± 0.21 | 12.33 ± 0.32* |
| HOMA-IR | 1.87 ± 0.24 | 2.78 ± 0.17* |
| Body weight (g) | 216 ± 3 | 219 ± 15 |
| Urine volume (ml/day/100g) | 4.1 ± 0.2 | 10.9 ± 0.7** |
| Urine osmolarity (mOsml/kg H2O) | 826 ± 110 | 499 ± 34* |