TABLE 4

Performance in the Morris water maze during trial 1 on days 1 and 2


Substance

Dose D1

Median Time to Reach Platform (D1, D2)

No. to Reach Platform

Behavior in Pool
mg/kg S
Vehicle 90, 70 2, 7 3, 4
cis-3-ACPBPA 10 59, 71 5, 8 3, 4
30 31**, 35* 7*, 9 4*, 4
100 85, 71 5, 6 3, 4
trans-3-ACPBPA 10 77, 44 5, 8 3, 4
30 82, 47 5, 8 3, 5

100
61*, 28*
6, 9
4, 6*
  • ** p < 0.01 and

  • * p < 0.05 compared with vehicle, nonparametric Mann-Whitney U test, unilateral comparison