TABLE 1

Blood calcium and creatinine profile

TNBS-treated mice were treated i.p. with dexamethasone and/or calcitriol from days 0 to 3 following the TNBS enema. Serum calcium and creatinine were determined following a 3-day treatment regimen. Data represent mean ± S.E.M. from three separate experiments (eight mice per group per experiment).




Serum Calcium

Serum Creatinine
mg / dl
Control 9.91 ± 0.32 0.95 ± 0.02
TNBS 9.95 ± 0.32 0.94 ± 0.03
Calcitriol (0.2 μg/kg) 11.24 ± 0.20a 0.96 ± 0.02b
Dex (0.6 mg/kg) 9.75 ± 0.21b 0.98 ± 0.02b
Dex (0.6 mg/kg) + calcitriol (0.2 μg/kg)
10.36 ± 0.26b
0.97 ± 0.02b
  • a P < 0.01 vs. TNBS-treated mice.

  • b Nonsignificant vs. TNBS-treated mice.