Agonist activity for inhibiting isoproterenol-stimulated cAMP accumulation in HEK T M2 cells The data are from Fig. 2a. The data represent the mean estimates ± S.E.M. The values in parentheses beside some of the estimates are the log means ± S.E.M.
Agonist | Emax | EC50 | Hill Slope | RAi | ||||
|---|---|---|---|---|---|---|---|---|
| (Emax EC50-carb)/(Emax-carb EC50) | q/p | τBKA/τAKB | ||||||
| % | μM | |||||||
| Carbachol | 39.8 ± 0.73 | 0.26 (–6.58 ± 0.064) | 1.31 ± 0.18 | 1.0 (0.0) | 1.0 (0.0) | 1.0 (0.0) | ||
| McN-A-343 | 23.2 ± 3.0 | 50 (–4.30 ± 0.069) | 1.14 ± 0.081 | 0.0030 (–2.52 ± 0.060) | 0.0030 (–2.53 ± 0.039) | 0.0022 (–2.65 ± 0.073) | ||