PT  - JOURNAL ARTICLE
AU  - Brotto, Marco
AU  - Abreu, Eduardo L.
TI  - Sarcopenia: Pharmacology of Today and Tomorrow
AID  - 10.1124/jpet.112.191759
DP  - 2012 Dec 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 540--546
VI  - 343
IP  - 3
4099  - http://jpet.aspetjournals.org/content/343/3/540.short
4100  - http://jpet.aspetjournals.org/content/343/3/540.full
SO  - J Pharmacol Exp Ther2012 Dec 01; 343
AB  - Sarcopenia remains largely undiagnosed and undertreated because of the lack of a universally accepted definition, effective ways to measure it, and identification of the outcomes that should guide treatment efficacy. An ever-growing number of clinicians and researchers along with funding and regulatory agencies have gradually recognized that sarcopenia is a human condition that requires both prevention and treatment. In this article, we review sarcopenia and its common and less known pharmacological treatments, attempt to define sarcopenia in its broader context, and present some new ideas for potential future treatment for this devastating condition.