TY - JOUR T1 - SOME PHARMACOLOGICAL PROPERTIES OF A SERIES OF ACETAMIDINES AND PROPIONAMIDINES JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 353 LP - 361 VL - 99 IS - 3 AU - Bradford N. Craver AU - Anne Cameron AU - Walter Barrett Y1 - 1950/07/01 UR - http://jpet.aspetjournals.org/content/99/3/353.abstract N2 - 1. The general pharmacological properties of a series of acetamidines and propionamidines have been presented. 2. A small minority of the amidines exhibited marked anticholinergic and somewhat less marked antihistaminic activity. The presumed structural requisites to those actions have been discussed. 3. A minority of the amidines comprised a second group that exhibited marked positive inotropic and chronotropic effects upon the perfused heart and the heartlung preparation. The presumed structural requisites to that action have been discussed in detail. ER -