RT Journal Article
SR Electronic
T1 PYRUVIC ACID ANTAGONISM TO BARBITURATE DEPRESSION
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 33
OP 37
VO 87
IS 1
A1 B. A. WESTFALL
YR 1946
UL http://jpet.aspetjournals.org/content/87/1/33.abstract
AB Data on 64 rabbits anesthetized with pentobarbital sodium (40 mgm./kgm. intravenously) indicate that: 1. Epinephrine increases the blood sugar level and shortens the sleeping time. 2. Insulin decreases the blood sugar level and shortens the sleeping time. 3. Intravenous injection of pyruvic acid decreases the depth of depression, and shortens the sleeping time (as defined in this study), but does not alter materially total depression time in rabbits.