PT  - JOURNAL ARTICLE
AU  - BENJAMIN De BOER
TI  - THE EFFECTS OF SODIUM SUCCINATE AND SUCROSE DIURESIS UPON PENTOBARBITAL ANESTHESIA
DP  - 1946 Dec 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 366--372
VI  - 88
IP  - 4
4099  - http://jpet.aspetjournals.org/content/88/4/366.short
4100  - http://jpet.aspetjournals.org/content/88/4/366.full
SO  - J Pharmacol Exp Ther1946 Dec 01; 88
AB  - Intravenous sodium succinate was more effective in counteracting pentobarbital anesthesia than intraperitoneal injection of the same quantity of succinate. Intravenous sucrose in large quantities was followed by a decrease in sleeping time comparable to that with intravenous succinate. Intravenous succinate or sucrose resulted in immediate diuresis. Intraperitoneal succinate was followed by a delayed excretion of urine similar to the antidiuretic effects of the control animals. The length of pentobarbital anesthesia appears to be correlated in general with the degree of diuresis produced by the various drugs used and the method of injection. 1946 by The American Society for Pharmacology and Experimental Therapeutics