PT  - JOURNAL ARTICLE
AU  - T. S. SAPPINGTON
AU  - N. HALPERIN
AU  - W. T. SALTER
TI  - IODINE IN BLOOD AND THYROID
DP  - 1944 Aug 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 331--339
VI  - 81
IP  - 4
4099  - http://jpet.aspetjournals.org/content/81/4/331.short
4100  - http://jpet.aspetjournals.org/content/81/4/331.full
SO  - J Pharmacol Exp Ther1944 Aug 01; 81
AB  - Although the measurement of iodine concentration in the blood plasma is of considerable interest in connection with the use of iodine-containing drugs, the best methods now available require nearly 40 cc. of blood for duplicate analyses of blood at physiological concentrations. This fact limits the use of such methods in man, and prohibits them in small animals. The present communication describes a micro-analytical technique which will yield duplicate analyses from 2 cc. of blood plasma or serum. The method involves the catalytic effect of iodide upon the reduction of ceric ion. The technique is colorimetric and is adaptable to standard photoelectric colorimeters such as are available in many laboratories at the present time.