PT - JOURNAL ARTICLE AU - LAWRENCE PETERS TI - A COMPARISON OF THE MECHANISM OF ACTION OF ARSENICALS AND SULFONAMIDES DP - 1943 Sep 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 32--36 VI - 79 IP - 1 4099 - http://jpet.aspetjournals.org/content/79/1/32.short 4100 - http://jpet.aspetjournals.org/content/79/1/32.full SO - J Pharmacol Exp Ther1943 Sep 01; 79 AB - The mode of action of sodium p-aminophenylarsonate (atoxyl) on E. coli appears to be similar to that of sulfonamides, since the same mechanisms of antagonism appear to be involved. The bacteriostatic and trypanocidal activities of m-amino-p-hydroxyphenylarsenoxide, `Mapharsen,' apparently are exerted through a different mechanism than that which is involved in the bacteriostatic action of sulfonamides.