RT Journal Article
SR Electronic
T1 THE REDUCTION OF <em>2,4,6</em>-TRINITROTOLUENE BY ANIMAL TISSUE IN VITRO
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 386
OP 393
VO 78
IS 4
A1 BENTON B. WESTFALL
YR 1943
UL http://jpet.aspetjournals.org/content/78/4/386.abstract
AB 1. It has been shown that extracts of animal tissues have the power of reducing symmetrical trinitrotoluene in vitro. At least a portion of the resulting product or products behaved as a diazotizable amino compound. 2. This reducing power was very largely destroyed by heating to 80°C. for 10 minutes. It was augmented by anaerobic conditions and very largely inhibited by oxygenation. 3. The reducing effect was partially removed by washing and restored by added succinate and discharged again by malonate. 4. These facts were interpreted as indicative of the presence of an enzyme concerned in the reduction.