TY - JOUR T1 - THE MODE OF ACTION OF NEOPRONTOSIL IN STREPTOCOCCUS INFECTIONS IN MICE JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 291 LP - 297 VL - 72 IS - 3 AU - J. T. LITCHFIELD, JR. AU - H. J. WHITE AU - E. K. MARSHALL, JR. Y1 - 1941/07/01 UR - http://jpet.aspetjournals.org/content/72/3/291.abstract N2 - The therapeutic activity of neoprontosil has been compared to that of sulfanilamide in a streptococcus infection in mice. Essentially the same blood concentration-time curve of sulfanilamide was obtained from both drugs by use of the drug-diet method of therapy. The results show that the entire therapeutic activity of neoprontosil depends on the sulfanilamide formed from it. ER -