PT - JOURNAL ARTICLE AU - J. M. ROBSON AU - A. I. S. MACPHERSON TI - RATE OF DISAPPEARANCE OF PITUITARY GONADOTROPHIN FROM THE BLOOD OF RABBITS DP - 1940 Dec 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 433--439 VI - 70 IP - 4 4099 - http://jpet.aspetjournals.org/content/70/4/433.short 4100 - http://jpet.aspetjournals.org/content/70/4/433.full SO - J Pharmacol Exp Ther1940 Dec 01; 70 AB - Gonadotrophin from horse pituitaries was injected intravenously into rabbits, and the disappearance of the hormone from the blood and excretion in the urine determined. Less than half of the injected amount could be detected in the serum within 6 hours, and only small amounts were present after 24 hours. Some 10 to 20 per cent of the injected hormone was recovered from the urine. A similar experiment performed on a child with a meningocoele showed that the hormone rapidly disappeared from the serum and that little of it was excreted in the urine.