PT  - JOURNAL ARTICLE
AU  - STEHLE, R. L.
AU  - MELVILLE, K. I.
AU  - OLDHAM, FRANCES K.
TI  - CHOLINE AS A FACTOR IN THE ELABORATION OF ADRENALINE
DP  - 1936 Apr 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 473--481
VI  - 56
IP  - 4
4099  - http://jpet.aspetjournals.org/content/56/4/473.short
4100  - http://jpet.aspetjournals.org/content/56/4/473.full
SO  - J Pharmacol Exp Ther1936 Apr 01; 56
AB  - The chemical relationship between choline and the side chain of adrenaline is pointed out. This relationship, together with the fact that the adrenal gland is especially rich in choline, indicates that choline may be important for the elaboration of both the autonomic hormones. The effects upon the blood pressure of the acetyl and catechol derivatives of choline and of the bases derived from choline by progressive demethylation are given. The acetyl derivatives of the same bases were also compared upon the isolated frog heart and upon the intestine of the rabbit.