RT Journal Article
SR Electronic
T1 THE CENTRAL ACTION OF ACETYLCHOLINE
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 446
OP 450
VO 56
IS 4
A1 GEORGE A. SILVER
A1 HENRY G. MORTON
YR 1936
UL http://jpet.aspetjournals.org/content/56/4/446.abstract
AB 1. Acetylcholine in concentrations of 2.0 to 4.0γ injected into the hypothalamic region of cats anesthetized with urethane caused a small rise in blood pressure followed by a sharp fall lasting one to two minutes. Similar injections into the lateral ventricle gave the same effect, but not so consistently. Control injections of saline were without effect. The fall of blood pressure was still produced after both vagi were cut. 2. Cardiac and respiratory irregularities occurred occasionally. 3. Intraventricular injections of acetylcholine into the unanesthetized cat caused drowsiness which lasted about one hour.