PT - JOURNAL ARTICLE AU - ERWIN E. NELSON TI - THE EFFECT OF PHLORIZIN UPON GLOMERULAR FILTRATION DP - 1935 Nov 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 372--376 VI - 55 IP - 3 4099 - http://jpet.aspetjournals.org/content/55/3/372.short 4100 - http://jpet.aspetjournals.org/content/55/3/372.full SO - J Pharmacol Exp Ther1935 Nov 01; 55 AB - In anesthetized rabbits kept in a relatively constant state of renal activity by the continuous infusion of either dextrose or sucrose solutions, the intravenous injection of phlorizin in doses of 200 mgm. per kilogram results in a more or less marked decrease in urine secretion. Calculation of the glomerular filtration indicates a marked reduction. These findings are presented as indicating evidence of an action of phlorizin on renal activity other than the well-known blocking of the tubular reabsorption of glucose.