PT  - JOURNAL ARTICLE
AU  - J. BRONFENBRENNER
AU  - H. NOGUCHI
TI  - ON THE RESISTANCE OF VARIOUS SPIROCHAETES IN CULTURES TO THE ACTION OF CHEMICAL AND PHYSICAL AGENTS
DP  - 1913 Mar 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 333--339
VI  - 4
IP  - 4
4099  - http://jpet.aspetjournals.org/content/4/4/333.short
4100  - http://jpet.aspetjournals.org/content/4/4/333.full
SO  - J Pharmacol Exp Ther1913 Mar 01; 4
AB  - The toxic effect exerted by the chemicals in the experiments is from twenty to one-hundred times greater if tested upon spirochaetes than it is against Colon-bacillus. The toxic effects of Salvarsan are increased from two to five times and possibly more in the presence of ensymes from the liver and especially from the blood. Spirochaetes suspended in physiological salt solution are sterilized by the temperature of 45°C. in from seven to ten minutes.