PT  - JOURNAL ARTICLE
AU  - J. CHRISTODOSS DAVID
TI  - THE ACTION OF DRUGS ON THE OXYGEN CONSUMPTION OF THE FROG'S ISOLATED AURICLE
DP  - 1930 Oct 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 229--234
VI  - 40
IP  - 2
4099  - http://jpet.aspetjournals.org/content/40/2/229.short
4100  - http://jpet.aspetjournals.org/content/40/2/229.full
SO  - J Pharmacol Exp Ther1930 Oct 01; 40
AB  - 1. A method is described for introducing drugs into an isolated auricle without disturbing the measurements of the oxygen consumption. 2. The action of three drugs on the oxygen consumption of the frog's isolated auricle was measured. 3. a. Adrenaline causes a percentage increase in oxygen consumption slightly greater than the percentage increase in frequency of beat. b. Strophanthin causes a decrease in both oxygen consumption and in frequency of beat; sub-lethal concentrations cause a temporary initial increase in oxygen consumption. c. Pilocarpine causes a percentage decrease in oxygen consumption that is greater than the percentage decrease in frequency of beat.