TY - JOUR T1 - STUDIES ON THE CARDIAC OUTPUT OF THE DOG II. THE INFLUENCE OF ATROPINE AND CARBON DIOXIDE ON THE CIRCULATION OF THE UNANESTHETIZED DOG JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 167 LP - 175 VL - 29 IS - 1 AU - E. K. MARSHALL, JR. Y1 - 1926/10/01 UR - http://jpet.aspetjournals.org/content/29/1/167.abstract N2 - The marked increase in pulse rate produced by administration of small doses of atropine is without influence on the minute volume of the circulation in the normal unanesthetized dog. A moderate increase of the carbon dioxide in the inspired air (3 to 5 per cent) does not change the minute volume, while breathing higher concentrations causes, if anything, a slight decrease. ER -