RT Journal Article
SR Electronic
T1 ON THE ACTION OF MAGNESIUM SULPHATE
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 87
OP 99
VO 2
IS 2
A1 S. A. MATTHEWS
A1 CLYDE BROOKS
YR 1910
UL http://jpet.aspetjournals.org/content/2/2/87.abstract
AB 1. These experiments tend to confirm the curare-like action of magnesium sulphate, particularly as described by the French authors. 2. Magnesium sulphate in doses sufficient to give marked action upon the motor endings, produces little effect upon the respiratory centre; but in larger doses, it causes depression of the centre. When administered to the unanæsthetized dog, primary stimulation of the respiratory movements were observed. 3. The action of magnesium upon the heart is best explained as that of a depression of the cardiac nervous mechanism involving particularly the accelerators.