RT Journal Article SR Electronic T1 THE MODE OF ACTION OF POTASSIUM UPON ISOLATED ORGANS JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 423 OP 447 VO 18 IS 6 A1 A. J. CLARK YR 1921 UL http://jpet.aspetjournals.org/content/18/6/423.abstract AB Rubidium acts as a perfect substitute to potassium in all of the isolated tissues examined; caesium acts as an imperfect substitute; thorium and uranium do not act as substitutes to potassium, but they act as irritants to the frog's heart and will induce automatic beats in hearts arrested by lack of potassium. The expenses of this research were defrayed by a grant from the Royal Society.