RT Journal Article
SR Electronic
T1 EFFECTS OF MERCURIAL DIURETICS ON THE RENAL TUBULAR TRANSPORT OF <em>p</em>-AMINOHIPPURATE AND DIODRAST IN THE CHIMPANZEE
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 759
OP 766
VO 180
IS 3
A1 FANELLI, GEORGE M.
A1 BOHN, DENNIS L.
A1 REILLY, SHEILA S.
YR 1972
UL http://jpet.aspetjournals.org/content/180/3/759.abstract
AB The mercurial diuretics mersalyl and chlormerodrin depress the maximal tubular transport of p-aminohippurate and Diodrast in the chimpanzee. This effect is not seen in the mongrel dog. The marked depression of the maximal tubular transport of p-aminohippurate and Diodrast is strikingly similar to that noted earlier in man. The organic acid transport system is apparently quite similar in the chimpanzee and man but fundamentally different in the lower species. © 1972 by The Williams &amp; Wilkins Co.