PT  - JOURNAL ARTICLE
AU  - AXELROD, JULIUS
AU  - COHN, CAL K.
TI  - METHYLTRANSFERASE ENZYMES IN RED BLOOD CELLS
DP  - 1971 Mar 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 650--654
VI  - 176
IP  - 3
4099  - http://jpet.aspetjournals.org/content/176/3/650.short
4100  - http://jpet.aspetjournals.org/content/176/3/650.full
SO  - J Pharmacol Exp Ther1971 Mar 01; 176
AB  - Catechol-O-methyltransferase, histamine-N-methyltransferase and a methanol-forming enzyme were identified in the red blood cells of humans and a variety of mammalian species. The properties of the transferase enzymes are described with respect to distribution in blood, co-factor requirements, products formed, species distribution and substrate specificity. The presence of the transferase enzyme in an easily accessible tissue in man makes possible a study of changes in these enzymes in different physiologic states, drug treatments and diseases. © 1971 by The Williams & Wilkins Co.