TY - JOUR T1 - A COMPARISON OF THE ACTION OF CERTAIN DRUGS UPON MUSCULAR WORK IN FROGS JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 129 LP - 139 VL - 17 IS - 2 AU - ELEANOR M. SCARBOROUGH Y1 - 1921/01/01 UR - http://jpet.aspetjournals.org/content/17/2/129.abstract N2 - 1. The action of a drug on striated muscle is shown more conclusively by comparison with previous conditions in the same muscle than by the use of two corresponding muscles, since these are not necessarily equally responsive. 2. The direct action of alcohol and veratrine on frog's muscle is to increase temporarily the amount of work done. 3. Cocaine directly depresses striated muscle without any preliminary increase in response. 4. On muscle which is becoming fatigued, caffeine has very slight restorative action, although an obvious increase in excitability occurs in unfatigued muscle. ER -