PT  - JOURNAL ARTICLE
AU  - JAMES S. NOONAN
AU  - PHILIP W. MTJRDICK
AU  - RICHARD S. RAY
TI  - A METHOD FOR DETECTING AMPHETAMINE USING GAS CHROMATOGRAPHY OF A HALOGENATED DERIVATIVE
DP  - 1969 Jul 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 205--209
VI  - 168
IP  - 1
4099  - http://jpet.aspetjournals.org/content/168/1/205.short
4100  - http://jpet.aspetjournals.org/content/168/1/205.full
SO  - J Pharmacol Exp Ther1969 Jul 01; 168
AB  - A sensitive, specific and rapid method for the detection of amphetamine in biologic fluids of horses is described. Amphetamine is extracted from alkaline biologic fluid into a mixture of hexane and iso-octane. The trichioroacetamide of amphetamine is made with trichloroacetyl chloride in the organic phase. The derivative is chromatographed on JXR (methyl silicone) and detected by electron capture. Amphetamine was readily detected in the plasma of horses given 300 mg of amphetamine sulfate s.c. The drug was detectable for seven hours postadministration. © 1969, by The Williams & Wilkins Company