RT Journal Article
SR Electronic
T1 ON THE ABSORPTION OF LOCAL ANESTHETICS THROUGH THE GENITO-URINARY ORGANS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 435
OP 448
VO 16
IS 6
A1 DAVID I. MACHT
YR 1921
UL http://jpet.aspetjournals.org/content/16/6/435.abstract
AB 1. The local anesthetics, cocain, alypin and apothesin, were studied in regard to their penetration through and absorption from various genito-urinary organs. 2. It was found that these drugs are more or less readily absorbed through the urethra, ureters, pelvis of the kidney, praeputium and vagina. 3. It was found that while the local anesthetics are readily and rapidly absorbed from the urethra, they are very poorly absorbed from the urinary bladder.